5.01.2007

Press Release: Zorro-LNA stops genetic disorders in their tracks - FierceBioReseacher

Press Release: Zorro-LNA stops genetic disorders in their tracks - FierceBioReseacher: "A study to appear in the June 2007 issue of The FASEB Journal describes a new agent, called 'Zorro-LNA,' which has the potential to stop genetic disorders in their tracks.

In the study, researchers from the Karolinska Institute in Stockholm, Sweden, describe how they developed Zorro-LNA to bind with both strands of a gene's DNA simultaneously, effectively disabling that gene. This development has clinical implications for virtually every human condition caused by or worsened by dominant defective genes. Examples include: Huntington's disease, familial high cholesterol, polycystic kidney disease, some instances of glaucoma and colorectal cancer, and neurofibromatosis, among others."