7.26.2007

Biolex Therapeutics Announces Positive Phase 2a Results for Hepatitis C Product Candidate Locteron(TM)

Biolex Therapeutics Announces Positive Phase 2a Results for Hepatitis C Product Candidate Locteron(TM): "PITTSBORO, NC -- 07/26/07 -- Biolex Therapeutics today announced successful initial results from the SELECT-1 Phase 2a clinical trial of Locteron(TM), the first controlled-release interferon alfa being developed for the treatment of chronic hepatitis C. In the 12-week Phase 2a trial, the combination of the highest dose of Locteron evaluated and the antiviral drug ribavirin achieved an early virologic response (EVR) in 100% of the hepatitis C patients treated. Importantly, the study results also indicated that patients receiving Locteron experienced side effects that were less frequent and less severe than those previously reported in clinical trials for the currently marketed pegylated interferons and for albumin-fused interferon (Albuferon(TM)) currently under development. Biolex is co-developing Locteron with its partner OctoPlus N.V."