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The radical, –OH.
Hydroxyl
From Wikipedia, the free encyclopedia
- This artical is about the hydroxyl functional group. For the Hydroxyl radical see Hydroxyl radical.
Hydroxyl in chemistry stands for a molecule consisting of an oxygen atom and a hydrogen atom connected by a covalent bond. The neutral form is a hydroxyl radical and the hydroxyl anion is called a hydroxide. When the oxygen atom is linked to a larger molecule the hydroxyl group is a functional group (HO– or –OH) .
[edit] Hydroxyl group
The term hydroxyl group is used to describe the functional group –OH when it is a substituent in an organic compound. Organic molecules containing a hydroxyl group are known as alcohols (the simplest of which have the formula CnH2n+1–OH).
[edit] Hydroxyl radical
The hydroxyl radical, ·OH, is the neutral form of the hydroxide ion. Hydroxyl radicals are highly reactive and consequently short lived; however, they form an important part of radical chemistry.
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hydroxyl group
From: The Columbia Encyclopedia, Sixth Edition | Date: 2007
hydroxyl group , in chemistry, functional group that consists of an oxygen atom joined by a single bond to a hydrogen atom. An alcohol is formed when a hydroxyl group is joined by a single bond to an alkyl group or aryl group . A metal hydroxide is formed when a hydroxyl group is joined to a metal (e.g., sodium hydroxide).
Author not available, HYDROXYL GROUP., The Columbia Encyclopedia, Sixth Edition 2007
The Columbia Encyclopedia, Sixth Edition. Copyright 2007 Columbia University Press
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Hydroxyl radical
From Wikipedia, the free encyclopedia
- This artical is about the Hydroxyl radical molecule. For the hydroxyl functional group see Hydroxyl
Hydroxyl in chemistry stands for a molecule consisting of an oxygen atom and a hydrogen atom connected by a covalent bond. The neutral form is a hydroxyl radical and the hydroxyl anion is called a hydroxide. When the oxygen atom is linked to a larger molecule the hydroxyl group is a functional group (HO– or –OH) .
Contents[hide] |
[edit] Hydroxyl group
The term hydroxyl group is used to describe the functional group –OH when it is a substituent in an organic compound. Organic molecules containing a hydroxyl group are known as alcohols (the simplest of which have the formula CnH2n+1–OH).
[edit] Hydroxyl radical
The hydroxyl radical, ·OH, is the neutral form of the hydroxide ion. Hydroxyl radicals are highly reactive and consequently short lived; however, they form an important part of radical chemistry. Most notably hydroxyl radicals are produced from the decomposition of hydro-peroxides (ROOH) or, in atmospheric chemistry, by the reaction of excited atomic oxygen with water. It is also an important radical formed in radiation chemistry, since it leads to the formation of hydrogen peroxide and oxygen, which can enhance corrosion and SCC in coolant systems subjected to radioactive environments.
In organic synthesis hydroxyl radicals are most commonly generated by photolysis of 1-Hydroxy-2(1H)-pyridinethione.
[edit] Atmospheric importance
The Hydroxyl radical is often referred to as the "detergent" of the troposphere because it reacts with many pollutants, often acting as the first step to their removal. The first reaction with many volatile organic compounds (VOCs) is the removal of a hydrogen atom forming water and an alkyl radical (R·).
- OH + RH → H2O + R·
The alkyl radical will typically react rapidly with oxygen forming a peroxy radical.
- R· + O2 → RO2
The fate of this radical in the troposphere is dependent on factors such as the amount of sunlight (light from the sun), pollution in the atmosphere and the nature of the alkyl radical that formed it.
[edit] Biological significance
The hydroxyl radical has a very short in vivo half-life of approx. 10 -9 s and a high reactivity. This makes it a very dangerous compound to the organism. Unlike superoxide, which can be detoxified by superoxide dismutase, the hydroxyl radical cannot be eliminated by an enzymatic reaction, as this would require its diffusion to the enzyme's active site. As diffusion is slower than the half-life of the molecule, it will react with any oxidizable compound in its vicinity. It can damage virtually all types of macromolecules: carbohydrates, nucleic acids (mutations), lipids ( lipid peroxidation) and amino acids (e.g. conversion of Phe to m-Tyrosine and o- Tyrosine). The only means to protect important cellular structures is the use of antioxidants such as glutathione and of effective repair systems.
