7.26.2007

ALSO NOTED: Geron faces critics' wrath;New diagnostics work targets prostate cancer; - FierceBioResearcher - Biotech research, Biotechnology research,

ALSO NOTED: Geron faces critics' wrath;New diagnostics work targets prostate cancer; - FierceBioResearcher - Biotech research, Biotechnology research, Bioinformatics: "The protein IKK-alpha, which is largely absent in a type of skin cancer, serves to guard a gene against mutations, according to researchers at the M.D. Anderson Cancer Center. 'Although IKK-alpha can protect the checkpoint gene 14-3-3-sigma from silencing, IKK-alpha itself is frequently impaired in cancer cells,' says Yinling Hu, Ph.D., senior author of the paper. 'We are going to define specific downstream targets of IKK-alpha involved in regulating DNA methylation of the checkpoint gene.' Release"